IMMUNE INACTIVATION OF ANTI-SIMIAN IMMUNODEFICIENCY VIRUS CHIMERIC ANTIGEN RECEPTOR T CELLS IN RHESUS MACAQUES

Immune inactivation of anti-simian immunodeficiency virus chimeric antigen receptor T cells in rhesus macaques

Chimeric antigen receptor (CAR) T cell therapies are being investigated as potential HIV cures and designed to target HIV reservoirs.Monoclonal antibodies (mAbs) targeting the simian immunodeficiency virus (SIV) envelope allowed us to investigate the potency of single-chain variable fragment (scFv)-based anti-SIV CAR T cells.In vitro, CAR T cells e

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Pelvic pseudocyst presenting with vaginal drainage of cerebrospinal fluid in an adolescent: A rare complication of ventriculoperitoneal shunt

Sodas The case report describes a 16-year-old female with a ventriculoperitoneal (VP) shunt due to congenital hydrocephalus.She presented with abdominal pain and vaginal leakage of cerebrospinal fluid (CSF).CT imaging demonstrated multiple intra-abdominal and pelvic CSF pseudocysts as well as possible erosion of the VP shunt into the vagina.She was

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Measuring the Cognitive Resources Consumed per Second for Real-time Lie-Production and Recollection: a Dual-tasking Paradigm

This research report presents a novel method of dual-tasking lie-detection.Novel software Follow Me was invented for a concurrent eye-hand coordination task during truth-telling/lying.Undergraduate participants were instructed to tell truths on Door Latch Hook questions about undergraduate school whereas they were instructed to tell lies on intervi

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